Caspase 1 Kit ELISA
Aperçu rapide pour Caspase 1 Kit ELISA (ABIN1168983)
Antigène
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Méthode de détection
Type de méthode
Gamme de detection
Application
Type d'échantillon
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Seuil minimal de détection
- 0.15 ng/mL
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Analytical Method
- Quantitative
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Specificité
- Detects mouse caspase-1 (proform as well as p10 and p20 domain).
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Réactivité croisée
- Souris
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Réactivité croisée (Details)
- Does not detect human caspase-1.
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Sensibilité
- 33 pg/mL
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Attributs du produit
- Standards are full lenght proteins.
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Plaque
- Pre-coated
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Restrictions
- For Research Use only
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Conseil sur la manipulation
- Avoid freeze/thaw cycles. Plate and reagents should reach room temperature before use.
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Stock
- 4 °C
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Stockage commentaire
- After standard reconstitution prepare aliquots and store at -20°C.
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Date de péremption
- 12 months
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: "Pharmacologic inhibition of IκB kinase activates immediate hypersensitivity reactions in mice." dans: The American journal of pathology, Vol. 183, Issue 1, pp. 96-107, (2013) (PubMed).
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: "Pharmacologic inhibition of IκB kinase activates immediate hypersensitivity reactions in mice." dans: The American journal of pathology, Vol. 183, Issue 1, pp. 96-107, (2013) (PubMed).
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- Caspase 1 (CASP1)
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Autre désignation
- Caspase-1
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Sujet
- Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and interleukin-18 (IL-18) and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3/NALP3 responds to a variety of agonists including crystals._x000D__x000D_This Caspase-1 (mouse) ELISA Kit can be used to measure caspase-1 (mouse) in cell culture supernatants. It is a quantitative detection method, alternative to Western blotting to measure caspase-1 secretion.
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UniProt
- P29452
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Pathways
- Apoptose, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
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